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County National Bank Logo
County National Bank

Hillsdale, Michigan

Massachusetts Institute of Technology (MIT) Logo
Massachusetts Institute of Technology (MIT)

Cambridge, Massachusetts

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Wright State University

Dayton, Ohio

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Brown Lab Research Fellow
Chronic lymphocytic leukemia (CLL) remains the most common leukemia of adults and is incurable.??Several novel therapies have substantially altered the treatment landscape for CLL, and studying the mechanisms of their activity, toxicity and resistance is of great interest.?? Our lab focuses on CLL, somatic and germline genomics of CLL and the mechanisms of these targeted therapies in CLL.?? CLL is one of the most familial of all cancers but the genetic basis of this remains poorly defined.?? We have previously shown that rare variants in ATM are associated with CLL, and this position will focus both on biological validation of the effects of those variants, as well as new gene discovery focused on the genomic study of familial CLL.?? We have a huge tissue bank of over 2500 CLL pati


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